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Product Details
BS-18037R
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
KLH conjugated synthetic peptide derived from human OTC, amino acids 31-130. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein A |
Storage buffer |
TBS with 1% BSA, 50% glycerol |
Contains |
0.03% ProClin 300 |
Storage conditions |
-20°C |
Target Information
This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ornithine carbamoyltransferase, mitochondrial; ornithine transcarbamylase; Ornithine transcarbamylase, mitochondrial; OTCase; sparse fur
Gene Aliases: AI265390; OCTD; OTC; Sf; spf
UniProt ID: (Human) P00480, (Mouse) P11725, (Rat) P00481
Entrez Gene ID: (Human) 5009, (Mouse) 18416, (Rat) 25611
Molecular Function:
transferase
metabolite interconversion enzyme
urea cycle
liver development
ornithine catabolic process
midgut development
response to zinc ion
citrulline biosynthetic process
response to insulin
arginine biosynthetic process via ornithine
response to drug
anion homeostasis
protein homotrimerization
response to biotin
ammonia homeostasis
cellular amino acid metabolic process
arginine biosynthetic process
ornithine metabolic process
cellular amino acid biosynthetic process
response to nutrient levels
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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