This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: ILADYLTLQE HYSSLKGLTL SWIGDGNNIL HSIMMSAAKF GMHLQAATPK GYEPDASVTK LAEQYAKENG TKLLLTNDPL EAAHGGNVLI TDTWISMGQE EEKKKRLQAF QGYQVTMKTA KVAASDWT
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 92%.
This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: mitochondrial; OCTD; ornithine carbamoyltransferase; Ornithine carbamoyltransferase, mitochondrial; Ornithine transcarbamylase; OTCase
Gene Aliases: OCTD; OTC
UniProt ID: (Human) P00480
Entrez Gene ID: (Human) 5009