Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Bioss
OTUB Polyclonal Antibody
FIGURE: 1 / 1
OTUB Antibody (BS-6236R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded Mouse brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with OTUB Polyclonal Antibody, Unconjugated (bs-6236R) at 1:200 overnight at 4°C, DAB staining.
Product Details
BS-6236R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human OTUB.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. This protein contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Deubiquitinating enzyme OTUB1; deubiquitinating enzyme OTUB1 {ECO:0000250|UniProtKB:Q7TQI3}; Deubiquitinating enzyme OTUB2; hOTU1; OTU domain, ubiquitin aldehyde binding 1; OTU domain, ubiquitin aldehyde binding 2; OTU domain-containing ubiquitin aldehyde-binding protein 1; OTU domain-containing ubiquitin aldehyde-binding protein 1 {ECO:0000250|UniProtKB:Q7TQI3}; OTU domain-containing ubiquitin aldehyde-binding protein 2; OTU-domain Ubal-binding 1; otub1 {ECO:0000312|EMBL:AAI66771.1}; otubain 1; Otubain-1; otubain-1 {ECO:0000250|UniProtKB:Q7TQI3}; Otubain-2; Ubiquitin thioesterase OTUB1; ubiquitin thioesterase OTUB1 {ECO:0000250|UniProtKB:Q7TQI3}; Ubiquitin thioesterase OTUB2; ubiquitin-specific protease otubain 1; ubiquitin-specific protease otubain 2; Ubiquitin-specific-processing protease OTUB1; ubiquitin-specific-processing protease OTUB1 {ECO:0000250|UniProtKB:Q7TQI3}; Ubiquitin-specific-processing protease OTUB2
Gene Aliases: 2010015L18Rik; 4930586I02Rik; AI413508; AI850305; AW557219; C14orf137; HSPC263; OTB1; OTB2; OTU1; OTU2; OTUB1; OTUB2
UniProt ID: (Human) Q96FW1, (Human) Q96DC9, (Mouse) Q7TQI3, (Rat) B2RYG6, (Mouse) Q9CQX0
Entrez Gene ID: (Human) 55611, (Human) 78990, (Mouse) 107260, (Rat) 293705, (Mouse) 68149, (Rat) 314405
adaptive immune response
DNA repair
cellular response to DNA damage stimulus
protein K48-linked deubiquitination
cellular response to interleukin-1
negative regulation of histone H2A K63-linked ubiquitination
negative regulation of double-strand break repair
protein deubiquitination
protein K11-linked deubiquitination
protein K63-linked deubiquitination
immune system process
proteolysis
cellular amino acid metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support