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Proteintech
OTUD5 Polyclonal Antibody
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Product Details
21002-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
OTUD5 Fusion Protein Ag15190 (202-561 aa encoded by BC028225)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: WFEKALRDK KGFIIKQMKE DGACLFRAVA DQVYGDQDMH EVVRKHCMDY LMKNADYFSN YVTEDFTTYI NRKRKNNCHG NHIEMQAMAE MYNRPVEVYQ YSTEPINTFH GIHQNEDEPI RVSYHRNIHY NSVVNPNKAT IGVGLGLPSF KPGFAEQSLM KNAIKTSEES WIEQQMLEDK KRATDWEATN EAIEEQVARE SYLQWLRDQE KQARQVRGPS QPRKASATCS SATAAASSGL EEWTSRSPRQ RSSASSPEHP ELHAELGMKP PSPGTVLALA KPPSPCAPGT SSQFSAGADR ATSPLVSLYP ALECRALIQQ MSPSAFGLND WDDDEILASV LAVSQQEYLD SMKKNKVPCR C (202-561 aa encoded by BC028225)
Target Information
This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: deubiquinating enzyme A; deubiquitinase A; Deubiquitinating enzyme A; DUBA; OTU domain containing 5; OTU domain-containing protein 5; unnamed protein product
Gene Aliases: AA407879; AI553596; BB114028; DUBA; DXImx46e; MCAND; OTUD5; Sfc7
UniProt ID: (Human) Q96G74, (Rat) Q2YDU3, (Mouse) Q3U2S4
Entrez Gene ID: (Human) 55593, (Rat) 363452, (Mouse) 54644
negative regulation of cytokine production
proteolysis
neural crest cell differentiation
protein deubiquitination
cell differentiation
negative regulation of type I interferon production
response to lipopolysaccharide
regulation of immune response
protein K63-linked deubiquitination
protein K48-linked deubiquitination
negative regulation of canonical Wnt signaling pathway
positive regulation of TORC1 signaling
positive regulation of TORC2 signaling
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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