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Invitrogen
OTUD5 Polyclonal Antibody
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Product Details
PA5-31723
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human OTUD5. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: A431.
Predicted reactivity: Mouse (98%), Rat (99%), Xenopus laevis (83%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: deubiquinating enzyme A; deubiquitinase A; Deubiquitinating enzyme A; DUBA; OTU domain containing 5; OTU domain-containing protein 5; unnamed protein product
Gene Aliases: DUBA; MCAND; OTUD5
UniProt ID: (Human) Q96G74
Entrez Gene ID: (Human) 55593
negative regulation of cytokine production
proteolysis
neural crest cell differentiation
protein deubiquitination
cell differentiation
negative regulation of type I interferon production
response to lipopolysaccharide
regulation of immune response
protein K63-linked deubiquitination
protein K48-linked deubiquitination
negative regulation of canonical Wnt signaling pathway
positive regulation of TORC1 signaling
positive regulation of TORC2 signaling
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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