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Invitrogen
OVOL2 Polyclonal Antibody
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FIGURE: 1 / 11
OVOL2 Antibody (PA5-115700) in ICC/IF
Immunocytochemistry analysis of OVOL2 in A549 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115700). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
Product Details
PA5-115700
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human OVOL2(Accession Q9BRP0), corresponding to amino acid residues V200-L250.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total OVOL2.
Target Information
DNA-binding protein that binds to the 5'-G[GCT]GGGGG-3' core sequence. Probably acts as a transcription regulator.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: hOvo2; MOVO-B zinc finger protein; MOVO-C zinc finger protein; mOvo2; OVO homolog-like 2; ovo-like 2; Transcription factor Ovo-like 2; Zinc finger OVO2; Zinc finger protein 339; Zinc finger protein mOVO
Gene Aliases: 1700108N11Rik; 1810007D21Rik; EUROIMAGE566589; M-OVO; M-OVO-A; M-OVO-B; MOVO; movo2; Ovo2; OVOL2; PPCD1; Zfp339; ZNF339
UniProt ID: (Human) Q9BRP0, (Mouse) Q8CIV7
Entrez Gene ID: (Human) 58495, (Rat) 296201, (Mouse) 107586
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
metal ion binding
transcription regulatory region DNA binding
nucleic acid binding
transcription factor activity, sequence-specific DNA binding
angiogenesis
neural crest cell migration
neural fold formation
heart looping
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
heart development
negative regulation of cell proliferation
epidermis development
epidermal cell differentiation
dorsal/ventral pattern formation
negative regulation of epithelial to mesenchymal transition
regulation of keratinocyte proliferation
negative regulation of transcription by competitive promoter binding
negative regulation of keratinocyte differentiation
positive regulation of keratinocyte differentiation
negative regulation of Notch signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
embryonic digestive tract morphogenesis
regulation of cell cycle
endocardium formation
heart trabecula formation
labyrinthine layer blood vessel development
negative regulation of stem cell proliferation
transcription, DNA-templated
regulation of transcription, DNA-templated
multicellular organism development
positive regulation of transcription from RNA polymerase II promoter
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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