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Immunogen sequence: MSEDSSALP WSINRDDYEL QEVIGSGATA VVQAAYCAPK KEKVAIKRIN LEKCQTSMDE LLKEIQAMSQ CHHPNIVSYY TSFVVKDELW LVMKLLSGGS VLDIIKHIVA KGEHKSGVLD ESTIATILRE VLEGLEYLHK NGQIHRDVKA GNILLGEDGS VQIADFGVSA FLATGGDITR NKVRKTFVGT PCWMAPEVME QVRGYDFKAD IWSFGITAIE LATGAAPYHK YPPMKVLMLT LQNDPPSLET GVQDKEMLKK YGKSFRKMIS LCLQKDPEKR PTAAELLRHK FFQKAKNKEF LQEKTLQRA (1-308 aa encoded by BC008726 )
OXSR1 serine/threonine kinase or (OSR1) is activated by osmotic stresses and regulates downstream protein kinases such as PAK1 in order to establish the sensor/signaling modules that initiate the cellular response to environmental stress. OXSR1 can be phosphorylated by ATM or ATR during the DNA damage process. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton.
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Protein Aliases: C6orf182; CEP57R; OTTHUMP00000209062; Oxidative stress-responsive 1 protein; oxidative-stress responsive 1; OXSR1; Serine/threonine-protein kinase OSR1
Gene Aliases: 2210022N24Rik; 2810422B09Rik; AI462649; AW209236; KIAA1101; mKIAA1101; OSR1; OXSR1