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Invitrogen
Oct-2 Polyclonal Antibody
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Product Details
PA5-142573
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence KQGLDSPSEHTDTER-C (aa 21-35).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
OCT-2 is a transcription factor belonging to the POU homeo-domain family that binds to the Ig gene octamer sites regulating B cell specific genes. OCT-2 protein expression is not restricted to B cells, although expression levels are much higher in these cells. OCT-2 expression is reported to be significantly greater in germinal center derived lymphomas, although other B cell lymphomas also display high levels of expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homeobox protein; Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Oct-2; Octamer-binding protein 2; Octamer-binding transcription factor 2; OTF-2; POU domain, class 2, transcription factor 2
Gene Aliases: Oct-2; OCT2; Oct2a; Oct2b; Otf-2; OTF2; POU2F2
UniProt ID: (Human) P09086, (Mouse) Q00196
Entrez Gene ID: (Human) 5452, (Mouse) 18987
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein domain specific binding
sequence-specific DNA binding
DNA binding
mature B cell differentiation
immunoglobulin secretion involved in immune response
transcription from RNA polymerase II promoter
humoral immune response
snRNA transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter
cell maturation
transcription, DNA-templated
regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
immunoglobulin secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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