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Invitrogen
Oncomodulin Polyclonal Antibody
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FIGURE: 1 / 1
Oncomodulin Antibody (PA5-47832) in WB
Western blot analysis of Oncomodulin in rat placenta tissue. Samples were incubated in Oncomodulin polyclonal antibody (Product # PA5-47832) using a dilution of 1 µg/mL followed by a HRP-conjugated Anti-Goat IgG secondary antibody. A specific band was detected for Oncomodulin at approximately 12 kDa (as indicated). This experiment was conducted under reducing conditions.
Product Details
PA5-47832
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat
Published species
C. elegans
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant rat Oncomodulin Met1-Ser109
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
In direct ELISAs, approximately 40% cross-reactivity with recombinant human Oncomodulin is observed.
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
Target Information
Oncomodulin, encoded by the OCM gene located on chromosome 7p22.3, is a protein that belongs to the parvalbumin family of calcium-binding proteins. It is most prominently found in the inner ear, as well as in certain retinal cells and regenerating neurons. Oncomodulin plays a crucial role in calcium ion homeostasis, which is vital for various cellular processes, including signal transduction, cellular motility, and growth. Notably, oncomodulin has been studied for its role in promoting nerve regeneration, particularly within the central nervous system, where it enhances axonal growth and neuronal repair. This makes it a molecule of significant interest for therapeutic strategies aiming to treat nerve injuries or neurodegenerative diseases. Beyond its neuroregenerative potential, oncomodulin is also expressed in some tumor types, which initially led to its association with cancer-related studies. Current research continues to explore its dual roles in both oncology and neurobiology to better understand its functional implications across different tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: OM; Oncomodulin; Parvalbumin beta
Gene Aliases: Ocm; OM; oncmodulin
UniProt ID: (Rat) P02631
Entrez Gene ID: (Rat) 25503
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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