This antibody is predicted to react with chicken, rat and Xenopus based on sequence homology.
OPN1MW encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness.
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Protein Aliases: cone dystrophy 5 (X-linked); GOP; Green cone photoreceptor pigment; green cone pigment; Green-sensitive opsin; Medium-wave-sensitive opsin 1; Medium-wave-sensitive opsin 2; Medium-wave-sensitive opsin 3; OPN1MW; Opsin 1 cone pigments medium-wave-sensitive 2; opsin 1 cone pigments medium-wave-sensitive 3; photopigment apoprotein
Gene Aliases: CBBM; CBD; COD5; GCP; GOP; OPN1MW; OPN1MW1; OPN1MW2; OPN1MW3
UniProt ID: (Human) P0DN77
Entrez Gene ID: (Human) 2652