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Product Details
17897-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Opticin Fusion Protein Ag12257 (1-332 aa encoded by BC074943)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MRLLAFLSL LALVLQETGT ASLPRKERKR REEQMPREGD SFEVLPLRND VLNPDNYGEV IDLSNYEELT DYGDQLPEVK VTSLAPATSI SPAKSTTAPG TPSSNPTMTR PTTAGLLLSS QPNHGLPTCL VCVCLGSSVY CDDIDLEDIP PLPRRTAYLY ARFNRISRIR AEDFKGLTKL KRIDLSNNLI SSIDNDAFRL LHALQDLILP ENQLEALPVL PSGIEFLDVR LNRLQSSGIQ PAAFRAMEKL QFLYLSDNLL DSIPGPLPLS LRSVHLQNNL IETMQRDVFC DPEEHKHTRR QLEDIRLDGN PINLSLFPSA YFCLPRLPIG RFT (1-332 aa encoded by BC074943)
Target Information
Opticin, also known as OPTC or OPT, is a 332 amino acid protein that is secreted into the extracellular matrix and contains seven LRR repeats. Expressed in skin and fetal liver and also present in ocular tissues, such as the retina, cornea and iris, opticin functions to bind collagen fibrils and, via this interaction, is thought to regulate fibril spacing, morphology and organization. Opticin is subject to post-translational O-glycosylation and may be associated with the pathogenesis of primary open angle glaucoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Oculoglycan; Opticin
Gene Aliases: OPT; OPTC
UniProt ID: (Human) Q9UBM4, (Mouse) Q920A0
Entrez Gene ID: (Human) 26254, (Mouse) 269120, (Rat) 304802
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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