|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||synthetic peptide MRALTLLALLALAALCIAGQAG, corresponding to amino acids 1-22 of Human Osteocalcin.|
|Storage buffer||whole serum|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Radioimmune Assays (RIA)||1:1900-1:2100|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-29477 detects Osteocalcin from human samples.
PA1-29477 has been successfully used in radioimmune assay applications.
The PA1-29477 immunogen is: Synthetic peptide: MRALTLLALLALAALCIAGQAG, corresponding to amino acids 1-22 of Human Osteocalcin.
Osteocalcin belongs to the osteocalcin/matrix Gla-protein family and constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are
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