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Proteintech
Osteoglycin Polyclonal Antibody, CoraLite® Plus 488
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Product Details
CL488-12755
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Osteoglycin fusion protein Ag3484
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MKTLQSTLL LLLLVPLIKP APPTQQDSRI IYDYGTDNFE ESIFSQDYED KYLDGKNIKE KETVIIPNEK SLQLQKDEAI TPLPPKKEND EMPTCLLCVC LSGSVYCEEV DIDAVPPLPK ESAYLYARFN KIKKLTAKDF ADIPNLRRLD FTGNLIEDIE DGTFSKLSLL EELSLAENQL LKLPVLPPKL TLFNAKYNKI KSRGIKANAF KKLNNLTFLY LDHNALESVP LNLPESLRVI HLQFNNIASI TDDTFCKAND TSYIRDRIEE IRLEGNPIVL GKHPNSFICL KRLPIGSYF
Target Information
Mimecan induces ectopic bone formation in conjunction with transforming growth factor beta. Mimecan is a small proteoglycan which contains tandem leucine-rich repeats. Mimecan is encoded by the OGN gene, a member of the small leucine-rich proteoglycan (SLRP) family of proteins. Mimecan induces ectopic bone formation in conjunction with transforming growth factor beta (TGF-beta-1 or TGF-beta-2) and may regulate osteoblast differentiation. High expression of mimecan protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants of mimecan. Alternatively spliced transcript variants that encode mimecan have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: corneal keratan sulfate proteoglycan; Mimecan; mimecan proteoglycan; OIF; Osteoglycin; Osteoinductive factor
Gene Aliases: 3110079A16Rik; mimecan; mimican; OG; OGN; OIF; SLRR3A
UniProt ID: (Human) P20774, (Mouse) Q62000
Entrez Gene ID: (Human) 4969, (Rat) 291015, (Mouse) 18295
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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