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Huabio
P2RX5 Polyclonal Antibody
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FIGURE: 1 / 3
P2RX5 Antibody (ER2001-36) in IHC (P)
Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-P2RX5 antibody. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (ER2001-36, 1:200) for 30 minutes at room temperature. Th... View More
Product Details
ER2001-36
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide within rat P2RX5 aa 400-455.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.4, with 0.2% BSA, 50% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Mmgt2 mediates Mg(2+) transport and may provide regulated pathways for Mg(2+) transport in the Golgi and post-Golgi organelles of epithelium-derived cells. Magnesium is an essential metal, but few selective transporters have been identified. The two separate gene products, Mmgt1 and Mmgt2, comprise the family that we have termed membrane Mg(2+) transporters (MMgTs), and the proteins reside in the membrane and mediate Mg(2+) transport. The transport of Mg(2+) is saturable and studies have identified that Mmgt2 fusion proteins reside in the Golgi complex and post-Golgi vesicles, including the early endosomes in COS-7 cells transfected with the respective tagged constructs. Among related pathways for Mmgt2 are transport and binding events, in particular, transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP receptor; Membrane magnesium transporter 2; membrane magnesium transporter 2 {ECO:0000250|UniProtKB:Q8R3L0}; MGC47755; mmgt2; mmgt2 {ECO:0000250|UniProtKB:Q8R3L0}; P2X purinoceptor 5; P2X5; Purinergic receptor; purinergic receptor P2X5-2
Gene Aliases: AI852046; Mmgt2; P2rx5; P2X5; RGD1311260
UniProt ID: (Rat) Q6P719, (Mouse) Q8R3L0, (Mouse) Q91VE2, (Rat) P51578
Entrez Gene ID: (Rat) 303211, (Mouse) 216829, (Mouse) 94045, (Rat) 113995
magnesium ion transmembrane transporter activity
copper ion transmembrane transporter activity
manganese ion transmembrane transporter activity
cobalt ion transmembrane transporter activity
nickel cation transmembrane transporter activity
inorganic cation transmembrane transporter activity
purinergic nucleotide receptor activity
extracellular ATP-gated cation channel activity
ATP binding
GTP binding
drug binding
zinc ion binding
ligand-gated ion channel
magnesium ion transport
transport
cation transport
cobalt ion transport
copper ion transport
manganese ion transport
nickel cation transport
copper ion transmembrane transport
nickel cation transmembrane transport
manganese ion transmembrane transport
cell surface receptor signaling pathway
neuronal action potential
purinergic nucleotide receptor signaling pathway
regulation of skeletal muscle tissue regeneration
protein homooligomerization
cation transmembrane transport
mitophagy in response to mitochondrial depolarization
skeletal muscle tissue growth
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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