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|Tested species reactivity||Guinea pig, Human, Mouse, Pig, Rat|
|Host / Isotype||Guinea pig / IgG|
|Immunogen||Synthetic peptide corresponding to residues D(460) S T S T D P K G L A Q L(472) of rat P2X2.|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||1:500|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-24623 detects P2X2 from human and rat samples. PA1-24623 is expected to cross react with mouse (100% conserved) and guinea pig (100% conserved) due to sequence homology.
PA1-24623 has been successfully used in immunohistochemistry (frozen), and Western blot procedures.
The PA1-24623 immunogen is a synthetic peptide corresponding to residues D(460) S T S T D P K G L A Q L(472) of rat P2X2.
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Six transcript variants encoding six distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ATP receptor; MGC129601; P2X purinoceptor 2; P2X Receptor, subunit 2; purinergic receptor P2X, ligand gated ion channel, 2; purinergic receptor P2X, ligand-gated ion channel, 2
DFNA41; P2RX2; P2X1R; P2X2; P2X2a