|Tested species reactivity||Human, Non-human primate, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||VEKQSTDSGAYSIG Corresponding to residues 383-397 of the carboxy-terminus of rat P2X3|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-30936 detects P2X3 from human, non-human primate, rat samples.
PA1-30936 has been successfully used in immunocytochemistry, immunohistochemistry, Western blot applications.
The PA1-30936 immunogen is: VEKQSTDSGAYSIG Corresponding to residues 383-397 of the carboxy-terminus of rat P2X3
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.