Search
Alomone Labs, LTD
P2X3 Receptor (extracellular) Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 4
P2X3 Receptor (extracellular) Antibody (APR-026-200UL) in ICC/IF
Expression of P2RX3 in rat PC12 cells - Cell surface detection of P2RX3 in intact living rat pheochromocytoma (PC12) cells. A. Extracellular staining with Anti-P2X3 Receptor (extracellular) Antibody (#APR-026), (1:50, red) followed by goat Anti-rabbit-AlexaFluor-594 secondary Antibody . B. DAPI was used as the counter stain (blue). C. Merge images of A and B.
Product Details
APR-026-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)KGFGRYANRVMDVSD, corresponding to amino acid residues 65-79 of rat P2X3 receptor, Extracellular
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Amount
160 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: ATP receptor; MGC129956; P2X purinoceptor 3; p2X receptor 3; P2X3; p2X3 purinoceptor; p2xr3; Purinergic receptor; purinergic receptor P2X3
Gene Aliases: 4930513E20Rik; P2rx3; P2X3
UniProt ID: (Rat) P49654, (Mouse) Q3UR32
Entrez Gene ID: (Rat) 81739, (Mouse) 228139
response to hypoxia
ion transport
cation transport
chemical synaptic transmission
neuromuscular synaptic transmission
response to temperature stimulus
response to heat
response to cold
response to mechanical stimulus
response to carbohydrate
response to organic substance
urinary bladder smooth muscle contraction
neuronal action potential
peristalsis
response to ATP
purinergic nucleotide receptor signaling pathway
regulation of synaptic plasticity
behavioral response to pain
sensory perception of taste
protein homooligomerization
cation transmembrane transport
transport
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support