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Invitrogen
P2X6 Polyclonal Antibody
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FIGURE: 1 / 1
P2X6 Antibody (PA5-87659) in WB
Western blot analysis of P2X6 in extracts of mouse pancreas. Samples were incubated with P2X6 Polyclonal antibody (Product # PA5-87659) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Product Details
PA5-87659
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-280 of human P2RX6 (NP_0011530261)
Conjugate
Form
Liquid
Concentration
0.47 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: WGLLDYKTEK WALLAKKGYQ ERDLEPQFSI ITKLKGVSVT QIKELGNRLW DVADFVKPPQ GENVFFLVTN FLVTPAQVQG RCPEHPSVPL ANCWVDEDCP EGEGGTHSHG VKTGQCVVFN GTHRTCEIWS WCPVESGVVP SRPLLAQAQN FTLFIKNTVT FSKFNFSKSN ALETWDPTYF KHCRYEPQFS PYCPVFRIGD LVAKAGGTFE DLALLGGSVG IRVHWDCDLD TGDSGCWPHY SFQLQEKSYN FRTATHWWEQ P; Positive Samples: Mouse pancreas; Cellular Location: Membrane, Multi-pass membrane protein
Target Information
P2rx6 encodes receptors that are members of the ligand-gated ion channel family that open in response to extracellular ATP. Each P2rx6 receptor is made up of a trimer of subunits (P2X1-7) all of which share the common structure of two transmembrane domains. The protein encoded by the P2rx6 gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. The P2rx6 gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants of P2rx6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP receptor; P2X purinoceptor 6; P2X6; P2XM; Purinergic receptor; Purinergic receptor P2X-like 1; purinergic receptor P2X-like 1, orphan receptor
Gene Aliases: P2rx6; P2rxl1; P2x6; P2xm
UniProt ID: (Mouse) O54803
Entrez Gene ID: (Mouse) 18440
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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