PA1-23558 detects Purinergic Receptor P2Y1 in Human samples.
P2Y1 is a Purinergic Receptor that causes a change in platelet shape and potentially leads to platelet aggregation by binding ADP, which results in the mobilization of intracellular calcium ions via activation of phospholipase C. This receptor also mediates the release of the relaxing factor nitric oxide and may be involved in the modulation of neuronal signal transmission. P2Y1 has been reported to be expressed in tissues throughout the body, particularly brain. ESTs have been isolated from human embryo, lung, and placenta libraries.
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Protein Aliases: ADP receptor; ATP receptor; P2 purinoceptor subtype Y1; P2Y purinoceptor 1; P2Y1; platelet ADP receptor; Purinergic receptor; purinergic receptor P2Y, G-protein coupled, 1
Gene Aliases: P2RY1; P2Y1
UniProt ID: (Human) P47900
Entrez Gene ID: (Human) 5028