|Tested species reactivity||Human, Mouse, Rat|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues of the human P2Y2 protein.|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
PA1-4517 detects P2Y purinoceptor 2 in human, rat and mouse samples.
PA1-4517 has been successfully used in Western blot and Immunohistochemistry procedures.
PA1-4517 immunogen is a synthetic peptide comprising of internal residues of the human P2Y2 protein. Reacts with rat and mouse P2Y2.
Maintain at 4°C for 3 months or at -20°C for longer periods. Avoid freeze/thaw cycles.
P2Y2 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlap in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to both adenosine and uridine nucleotides. It may participate in control of the cell cycle of endometrial carcinoma cells. P2Y2 is also a morphogen receptor that potentiates neurotrophin signaling in neuronal development and regeneration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
P2Y4 Nucleotide Receptor in Neuronal Precursors Induces Glutamatergic Subtype Markers in Their Descendant Neurons.
PA1-4517 was used in western blot to elucidate induction of glutamatergic subtype markers in their descendant neurons by P2Y4 nucleotide receptor in neuronal precursors
|Uda Y,Xu S,Matsumura T,Takei Y||Stem cell reports (6:474)||2016|