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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the second cytoplasmic loop of human P2Y6.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.7|
|Contains||0.01% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-20617 detects P2Y6 in human samples.
PA1-20617 has been successfully used in immunohistochemistry (paraffin) procedures.
The PA1-20617 immunogen is a synthetic peptide corresponding to the second cytoplasmic loop of human P2Y6.
P2Y6 belongs to the family of G protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. P2Y6 expression has been documented in various blood cells, bone marrow, brain, colon, heart, kidney, ovary, placenta, spleen,and thymus. ESTs have been isolated from cervix, embryo, eye, kidney, liver/spleen, placenta, and vessel libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
G-coupled nucleotide receptor; MGC15335; P2 purinoceptor; P2Y purinoceptor 6; P2Y6; P2Y6 receptor; pyrimidinergic receptor P2Y, G-protein coupled, 6
P2RY6; P2Y6; PP2891