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Invitrogen
P2Y6 Polyclonal Antibody
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Product Details
PA5-112121
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to the center region of the Human P2RY6
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
P2Y6 belongs to the family of G protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. P2Y6 expression has been documented in various blood cells, bone marrow, brain, colon, heart, kidney, ovary, placenta, spleen and thymus. ESTs have been isolated from cervix, embryo, eye, kidney, liver/spleen, placenta, and vessel libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G-coupled nucleotide receptor; G-protein coupled receptor; long splice variant; MGC15335; P2 purinoceptor; P2Y purinoceptor 6; p2y3 and chick; p2y3 receptor; P2Y6; P2Y6 receptor; Purinoceptor p2y6; pyrimidinergic receptor P2Y, G-protein coupled, 6; short splice variant; unnamed protein product
Gene Aliases: P2RY6; P2Y6; PP2891
UniProt ID: (Human) Q15077
Entrez Gene ID: (Human) 5031
phagocytosis
signal transduction
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
transepithelial chloride transport
positive regulation of inositol trisphosphate biosynthetic process
G-protein coupled purinergic nucleotide receptor signaling pathway
positive regulation of release of sequestered calcium ion into cytosol
positive regulation of ERK1 and ERK2 cascade
cellular response to prostaglandin E stimulus
cellular response to purine-containing compound
cellular response to oxygen-containing compound
positive regulation of vascular smooth muscle cell proliferation
cellular response to pyrimidine ribonucleotide
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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