Search
Invitrogen
P2Y6 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
PA5-34093
Product Specifications
Species Reactivity
Bovine,
Hamster,
Human,
Non-human primate,
Pig,
Rabbit,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 17 amino acid peptide from 2nd cytoplasmic domain of human P2RY6 / P2Y6.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Rat, Hamster, Bovine, Rabbit, Pig (100%).
Target Information
P2Y6 belongs to the family of G protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. P2Y6 expression has been documented in various blood cells, bone marrow, brain, colon, heart, kidney, ovary, placenta, spleen and thymus. ESTs have been isolated from cervix, embryo, eye, kidney, liver/spleen, placenta, and vessel libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: G-coupled nucleotide receptor; G-protein coupled receptor; long splice variant; MGC15335; P2 purinoceptor; P2Y ATP receptor 6; P2Y purinoceptor 6; p2y3 and chick; p2y3 receptor; P2Y6; P2Y6 nucleotide receptor; P2Y6 receptor; purinergic P2Y6 receptor; Purinoceptor p2y6; pyrimidinergic receptor P2Y, G-protein coupled, 6; short splice variant; unnamed protein product
Gene Aliases: P2RY6; P2Y6; P2Y6R; PP2891
UniProt ID: (Human) Q15077, (Rat) Q63371
Entrez Gene ID: (Bovine) 539703, (Human) 5031, (Rabbit) 100358580, (Pig) 100512849, (Rat) 117264, (Chinese hamster) 100752781
phagocytosis
signal transduction
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
transepithelial chloride transport
positive regulation of inositol trisphosphate biosynthetic process
G-protein coupled purinergic nucleotide receptor signaling pathway
positive regulation of release of sequestered calcium ion into cytosol
positive regulation of ERK1 and ERK2 cascade
cellular response to prostaglandin E stimulus
cellular response to purine-containing compound
cellular response to oxygen-containing compound
positive regulation of vascular smooth muscle cell proliferation
cellular response to pyrimidine ribonucleotide
positive regulation of smooth muscle cell migration
cellular response to organic cyclic compound
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support