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Proteintech
P3H3 Polyclonal Antibody
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Product Details
16023-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
P3H3 Fusion Protein Ag8850 (223-605 aa encoded by BC017217)
Conjugate
Form
Liquid
Concentration
0.16 mg/mL
Amount
24 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: RALNQYQAQ LGEPRPGLGP REDIQRFILR SLGEKRQLYY AMEHLGTSFK DPDPWTPAAL IPEALREKLR EDQEKRPWDH EPVKPKPLTY WKDVLLLEGV TLTQDSRQLN GSERAVLDGL LTPAECGVLL QLAKDAAGAG ARSGYRGRRS PHTPHERFEG LTVLKAAQLA RAGTVGSQGA KLLLEVSERV RTLTQAYFSP ERPLHLSFTH LVCRSAIEGE QEQRMDLSHP VHADNCVLDP DTGECWREPP AYTYRDYSGL LYLNDDFQGG DLFFTEPNAL TVTARVRPRC GRLVAFSSGV ENPHGVWAVT RGRRCALALW HTWAPEHREQ EWIEAKELLQ ESQEEEEEEE EEMPSKDPSP EPPSRRHQRV QDKTGRAPRV REEL (223-605 aa encoded by B C017217)
Target Information
The protein encoded by this gene belongs to the leprecan family of proteoglycans, which function as collagen prolyl hydroxylases that are required for proper collagen biosynthesis, folding and assembly. This protein, like other family members, is thought to reside in the endoplasmic reticulum. Epigenetic inactivation of this gene is associated with breast and other cancers, suggesting that it may function as a tumor suppressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: gene rich cluster, B; leprecan-like 2; Leprecan-like protein 2; procollagen-proline 3-dioxygenase; Prolyl 3-hydroxylase 3; Protein B; unnamed protein product
Gene Aliases: BC016431; GRCB; HSU47926; LEPREL2; P3H3
UniProt ID: (Human) Q8IVL6, (Mouse) Q8CG70
Entrez Gene ID: (Human) 10536, (Rat) 297595, (Mouse) 14789
iron ion binding
protein binding
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
procollagen-proline 3-dioxygenase activity
L-ascorbic acid binding
metal ion binding
dioxygenase activity
molecular_function
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
extracellular matrix glycoprotein
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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