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Invitrogen
P4HA3 Polyclonal Antibody
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Product Details
PA5-89422
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-110 of human P4HA3 (NP_8789071)
Conjugate
Form
Liquid
Concentration
1.43 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DPERAAARGD TFSALTSVAR ALAPERRLLG LLRRYLRGEE ARLRDLTRFY DKVLSLHEDS TTPVANPLLA FTLIKRLQSD WRNVVHSLEA S; Positive Samples: 293T; Cellular Location: Endoplasmic reticulum lumen
Target Information
Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 4-PH alpha-3; C-P4H alpha III; collagen prolyl 4-hydroxylase alpha 3; collagen prolyl 4-hydroxylase alpha III subunit; collagen prolyl 4-hydroxylase alpha(III); procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III; Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3; Prolyl 4-hydroxylase subunit alpha-3; prolyl 4-hydroxylase, alpha polypeptide III
Gene Aliases: D930031A02Rik; P4HA3; UNQ711/PRO1374
UniProt ID: (Human) Q7Z4N8, (Rat) Q6W3E9
Entrez Gene ID: (Human) 283208, (Mouse) 320452, (Rat) 361612
procollagen-proline 4-dioxygenase activity
iron ion binding
protein binding
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
L-ascorbic acid binding
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
metal ion binding
dioxygenase activity
protein modifying enzyme
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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