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Invitrogen
LIM1 Polyclonal Antibody
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Product Details
PA1-41588
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptides corresponding to amino acids 149-165, 175-182, and 395-412 of human Lim-1.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Suggested positive control: human muscle tissue, human skeletal muscle protein.
Target Information
This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in control of differentiation and development of neural and lymphoid cells. A similar protein in mice is an essential regulator of the vertebrate head organizer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hLim-1; Homeobox protein Lim-1; LHX-1; LIM homeobox protein 1; LIM/homeobox protein Lhx1; MGC126723; MGC138141; unnamed protein product
Gene Aliases: LHX1; LIM-1; LIM1
UniProt ID: (Human) P48742
Entrez Gene ID: (Human) 3975
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter proximal region sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
sequence-specific DNA binding
metal ion binding
sequence-specific double-stranded DNA binding
urogenital system development
metanephros development
ureteric bud development
branching involved in ureteric bud morphogenesis
gastrulation with mouth forming second
ectoderm formation
endoderm formation
kidney development
mesonephros development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
cell-cell signaling
pattern specification process
nervous system development
endoderm development
motor neuron axon guidance
anatomical structure morphogenesis
post-embryonic development
embryonic pattern specification
organ morphogenesis
anterior/posterior axis specification
anterior/posterior pattern specification
dorsal/ventral pattern formation
regulation of gene expression
retina layer formation
spinal cord development
ventral spinal cord development
spinal cord association neuron differentiation
telencephalon development
cerebellum development
cerebellar Purkinje cell differentiation
forebrain regionalization
cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation
cell differentiation
neuron differentiation
somite rostral/caudal axis specification
metanephric part of ureteric bud development
oviduct epithelium development
uterine epithelium development
nephric duct elongation
positive regulation of embryonic development
cellular response to fibroblast growth factor stimulus
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
mesendoderm development
anatomical structure formation involved in morphogenesis
embryonic viscerocranium morphogenesis
system development
pronephros development
retina development in camera-type eye
embryonic retina morphogenesis in camera-type eye
uterus development
oviduct development
cervix development
vagina development
head development
epithelium development
paramesonephric duct development
comma-shaped body morphogenesis
S-shaped body morphogenesis
renal vesicle morphogenesis
mesonephric tubule development
mesonephric duct development
nephric duct morphogenesis
ureter morphogenesis
metanephric glomerulus development
metanephric comma-shaped body morphogenesis
metanephric renal vesicle morphogenesis
metanephric S-shaped body morphogenesis
primitive streak formation
positive regulation of branching involved in ureteric bud morphogenesis
dorsal spinal cord interneuron posterior axon guidance
lateral motor column neuron migration
positive regulation of gastrulation
positive regulation of anterior head development
positive regulation of nephron tubule epithelial cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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