PA1-41633 detects Exportin-4 in chicken, chimpanzee, rhesus monkey, canine, human, rat and mouse samples.
This antibody is predicted to react with bovine, xenopus, and zebrafish based on sequence homology.
Suggested positive control: Jurkat whole cell lysate.
Nuclear transport receptors of karyopherin/importin-beta superfamily mediate various transport pathways between nucleus and cytoplasm. Exportin-4 is a novel mammalian member of this family. It is a RanGTP-binding protein consisting of N-terminal RanGTP-binding motif. It functions as a nuclear export receptor for eIF-5A and also might function as an export adapter in RNA export. It is also involved in nuclear export of Smad3 and regulation of Smad signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Exp4; Exportin-4; FLJ13046
Gene Aliases: B430309A01Rik; exp4; KIAA1721; mKIAA1721; RCJMB04_1f17; XPO4
Molecular Function: transfer/carrier protein