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Invitrogen
APOBEC3D/APOBEC3F Polyclonal Antibody
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FIGURE: 1 / 2
APOBEC3D/APOBEC3F Antibody (PA5-101777) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded APOBEC3D/APOBEC3F in rat lung tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with APOBEC3D/APOBEC3F polyclonal antibody (Product # PA5-101777) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Product Details
PA5-101777
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human APOBEC3D(Accession Q96AK3), corresponding to amino acid residues I41-R91.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total APOBEC3D/F.
Target Information
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A3D; A3F; apolipoprotein B editing enzyme catalytic polypeptide-like 3F; apolipoprotein B mRNA editing enzyme cytidine deaminase; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3E pseudogene; Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F; bK150C2.4; bK150C2.9; cytidine deaminase; DNA dC->dU-editing enzyme APOBEC-3D; DNA dC->dU-editing enzyme APOBEC-3F; induced upon T-cell activation; probable DNA dC->dU-editing enzyme APOBEC-3D; unnamed protein product
Gene Aliases: A3D; A3DE; A3F; APOBEC3D; APOBEC3DE; APOBEC3E; APOBEC3F; ARP6; ARP8; BK150C2.4.MRNA; KA6
UniProt ID: (Human) Q96AK3, (Human) Q8IUX4
Entrez Gene ID: (Human) 140564, (Human) 200316
positive regulation of defense response to virus by host
immune system process
negative regulation of transposition, RNA-mediated
negative regulation of macromolecule biosynthetic process
base conversion or substitution editing
cytidine to uridine editing
hypomethylation of CpG island
clearance of foreign intracellular DNA
negative regulation of viral genome replication
innate immune response
negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
negative regulation of viral process
defense response to virus
DNA cytosine deamination
antiviral innate immune response
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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