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Invitrogen
SIX4 Polyclonal Antibody
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FIGURE: 1 / 2
SIX4 Antibody (PA5-103902) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded SIX4 in human spleen tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with SIX4 polyclonal antibody (Product # PA5-103902) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Product Details
PA5-103902
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SIX4(Accession Q9UIU6), corresponding to amino acid residues R275-S325.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total SIX4.
Target Information
SIX4 gene ontology annotations related to this gene include anatomical structure development; embryonic cranial skeleton morphogenesis; fungiform papilla morphogenesis; generation of neurons; inner ear morphogenesis; male gonad development; male sex determination; metanephric mesenchyme development; myoblast migration; myotome development; negative regulation of neuron apoptotic process; negative regulation of satellite cell differentiation; negative regulation of transcription, DNA-templated; olfactory placode formation; pharyngeal system development; positive regulation of branching involved in ureteric bud morphogenesis; positive regulation of ureteric bud formation; protein localization to nucleus; regulation of branch elongation involved in ureteric bud branching; regulation of epithelial cell proliferation; regulation of protein localization; regulation of synaptic growth at neuromuscular junction; sarcomere organization; skeletal muscle fiber differentiation; thymus development; trigeminal ganglion development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Homeobox protein SIX4; Sine oculis homeobox homolog 4; sine oculis-related homeobox 4 homolog; Skeletal muscle-specific ARE-binding protein AREC3
Gene Aliases: AI047561; AREC3; SIX4; TrexBF
UniProt ID: (Human) Q9UIU6, (Mouse) Q61321
Entrez Gene ID: (Human) 51804, (Mouse) 20474, (Rat) 299138
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein binding
homeodomain transcription factor
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
skeletal muscle tissue development
regulation of synaptic growth at neuromuscular junction
male gonad development
anatomical structure morphogenesis
regulation of gene expression
male sex determination
olfactory placode formation
regulation of protein localization
protein localization to nucleus
inner ear morphogenesis
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
tongue development
sarcomere organization
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
male sex differentiation
thymus development
generation of neurons
embryonic cranial skeleton morphogenesis
embryonic skeletal system morphogenesis
regulation of epithelial cell proliferation
myoblast migration
pharyngeal system development
myotome development
fungiform papilla morphogenesis
trigeminal ganglion development
metanephric mesenchyme development
regulation of branch elongation involved in ureteric bud branching
positive regulation of ureteric bud formation
positive regulation of branching involved in ureteric bud morphogenesis
skeletal muscle fiber differentiation
negative regulation of satellite cell differentiation
transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
anatomical structure development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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