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Invitrogen
ULK4 Polyclonal Antibody
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FIGURE: 1 / 2
ULK4 Antibody (PA5-104130) in ICC/IF
Immunofluorescent analysis of ULK4 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and ULK4 polyclonal antibody (Product # PA5-104130) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Product Details
PA5-104130
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ULK4(Accession Q96C45), corresponding to amino acid residues M766-R816.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total ULK4.
Target Information
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. ULK4 (unc-51-like kinase 4) is a 1,275 amino acid protein that contains one protein kinase domain and one HEAT repeat and belongs to the Ser/Thr protein kinase family. Although containing what is thought to be a catalytically inactive domain, ULK4 may play a role in the ATP-dependent phosphorylation of target proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Serine/threonine-protein kinase ULK4; unc-51 like kinase 4; Unc-51-like kinase 4; unnamed protein product
Gene Aliases: 4932415A06Rik; A730098P15; FAM7C1; REC01035; RGD1565726; ULK4
UniProt ID: (Human) Q96C45, (Mouse) Q3V129
Entrez Gene ID: (Human) 54986, (Mouse) 209012, (Rat) 363167
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
protein serine kinase activity
transferase activity, transferring phosphorus-containing groups
molecular_function
non-receptor serine/threonine protein kinase
protein modifying enzyme
microtubule cytoskeleton organization
regulation of signal transduction
regulation of neuron projection development
protein kinase C deactivation
regulation of MAPK cascade
regulation of JNK cascade
regulation of p38MAPK cascade
regulation of neuron migration
epithelial cilium movement
protein phosphorylation
phosphorylation
ventricular system development
corpus callosum development
cilium morphogenesis
regulation of protein kinase C signaling
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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