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Invitrogen
MCT2 Polyclonal Antibody
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Product Details
PA5-112712
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Monocarboxylate transporter 2 protein (197-279AA)
Conjugate
Form
Liquid
Concentration
2 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Tissues with few or no mitochondria, such as erythrocytes and tumor cells, depend largely on glycolysis to generate ATP. The major end products of glycolysis, pyruvate and lactate, must be eliminated from these cells to enable continued glycolytic flux and prevent toxic effects. H+/monocarboxylate transporters mediate the transport of lactate and pyruvate. Human MCT2 has a high affinity for the transport of pyruvate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MCT 2; monocarboxylate transporter; Monocarboxylate transporter 2; solute carrier family 16 (monocarboxylate transporter), member 7; Solute carrier family 16 member 7; solute carrier family 16, member 7 (monocarboxylic acid transporter 2); unnamed protein product
Gene Aliases: MCT2; SLC16A7
UniProt ID: (Human) O60669
Entrez Gene ID: (Human) 9194
pyruvate secondary active transmembrane transporter activity
protein binding
monocarboxylic acid transmembrane transporter activity
lactate transmembrane transporter activity
symporter activity
secondary active monocarboxylate transmembrane transporter activity
transmembrane transporter activity
identical protein binding
pyruvate transmembrane transporter activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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