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Invitrogen
FBXL5 Polyclonal Antibody
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Product Details
PA5-113529
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human F-box/LRR-repeat protein 5 protein (1-310AA)
Conjugate
Form
Liquid
Concentration
0.45 mg/mL
Amount
45 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternative splicing of this gene generates 2 transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: contains leucine rich repeats; F-box and leucine-rich repeat protein 5; F-box protein FBL4/FBL5; F-box/LRR-repeat protein 5; p45SKP2-like protein; unnamed protein product
Gene Aliases: FBL4; FBL5; FBXL5; Fir4; FLR1
UniProt ID: (Human) Q9UKA1, (Mouse) Q8C2S5
Entrez Gene ID: (Human) 26234, (Mouse) 242960
protein ubiquitination
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
iron ion homeostasis
positive regulation of cellular protein catabolic process
cellular iron ion homeostasis
protein catabolic process
positive regulation of protein catabolic process
cation homeostasis
multicellular organismal iron ion homeostasis
inorganic ion homeostasis
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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