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          • Primary Antibodies ›
          • Nesprin 2 Antibodies

          Invitrogen

          Nesprin 2 Polyclonal Antibody

          View all (9) Nesprin 2 antibodies

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          Cite Nesprin 2 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          Nesprin 2 Antibody in Western Blot (WB)
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          Nesprin 2 Antibody in Western Blot (WB)
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          FIGURE: 1 / 2

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          Nesprin 2 Antibody (PA5-119304) in WB

          Western blot analysis of Nesprin 2 using Nesprin 2 Polyclonal Antibody (Product # PA5-119304) at a dilution of 1 µg/mL. Lane 1: Human Lung lysate; Lane 2: A431 cell lysate; Lane 3: Porcine Kidney lysate; Lane 4: Porcine Stomach lysate. Secondary antibody used is HRP-Goat anti-Rabbit IgG polyclonal antibody at a dilution of 0.2 µg/mL. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Nesprin 2 Antibody in Western Blot (WB)
          Nesprin 2 Antibody in Western Blot (WB)
          Nesprin 2 Polyclonal Antibody

          Product Details

          PA5-119304

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.01-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Pig

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein Nesprin 2. The antigen corresponds to amino acid range 6-296 of the target protein.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          200 µg

          Purification

          Antigen affinity chromatography, Protein A

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.05% ProClin 300

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2903802

          Target Information

          The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: actin-binding protein; actin-binding protein associated with nuclear envelope; cytoskeletal protein; KASH domain-containing protein 2; KASH2; MGC96690; nesprin 2; Nesprin-2; nesprin-2 spectrin repeats 3-54; Nuclear envelope spectrin repeat protein 2; Nucleus and actin connecting element protein; polytrophin; Protein NUANCE; short isoform; spectrin repeat containing, nuclear envelope 2; Synaptic nuclear envelope protein 2; synaptic nuclei expressed gene 2; Syne-2; unnamed protein product

          View more View less

          Gene Aliases: EDMD5; KASH2; KIAA1011; Nesp2; Nesprin-2; NUA; NUANCE; SYNE-2; SYNE2; TROPH

          View more View less

          UniProt ID: (Human) Q8WXH0

          View more View less

          Entrez Gene ID: (Pig) 100524661, (Human) 23224

          View more View less

          Function(s)
          actin binding protein binding cytoskeleton-nuclear membrane anchor activity
          Process(es)
          nuclear migration nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration positive regulation of cell migration nuclear migration along microfilament centrosome localization regulation of cilium assembly
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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