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Invitrogen
DDIT4 Polyclonal Antibody
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FIGURE: 1 / 3
DDIT4 Antibody (PA5-13253) in IHC (P)
Immunohistochemistry analysis of DDIT4 in formalin fixed and paraffin embedded human pancreas tissue. Samples were incubated with DDIT4 polyclonal antibody (Product # PA5-13253) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-13253
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 198-227 amino acids from the C-terminal region of human DDIT4
Conjugate
Form
Liquid
Concentration
2 mg/mL
Amount
800 µg
Purification
Size-exclusion - Dialysis, Ammonium sulfate precipitation
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with bovine, mouse and rat based on sequence homology.
Target Information
DDIT4 gene ontology annotations related to this gene include cellular response to dexamethasone stimulus; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; negative regulation of glycolytic process; negative regulation of TOR signaling; protein-containing complex disassembly; reactive oxygen species metabolic process; response to hypoxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DNA damage-inducible transcript 4 protein; evolutionarily conserved protein; HIF-1 responsive protein RTP801; hRTP801; Protein regulated in development and DNA damage response 1; REDD-1; RP11-442H21.1; unnamed protein product
Gene Aliases: DDIT4; Dig2; REDD-1; REDD1; RTP801
UniProt ID: (Human) Q9NX09
Entrez Gene ID: (Human) 54541
response to hypoxia
neuron migration
apoptotic process
brain development
negative regulation of signal transduction
neuron differentiation
negative regulation of TOR signaling
protein-containing complex disassembly
intracellular signal transduction
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of glycolytic process
neurotrophin TRK receptor signaling pathway
defense response to virus
cellular response to dexamethasone stimulus
reactive oxygen species metabolic process
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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