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          • Primary Antibodies ›
          • COG8 Antibodies

          Invitrogen

          COG8 Polyclonal Antibody

          1 Reference
          View all (5) COG8 antibodies

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          Cite COG8 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          COG8 Antibody in Immunocytochemistry (ICC/IF)
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          COG8 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          COG8 Antibody (PA5-29126) in ICC/IF

          Immunocytochemistry analysis of COG8 in methanol-fixed A431. Samples were incubated with COG8 polyclonal antibody (Product # PA5-29126) using a dilution of 1:500. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          COG8 Antibody in Immunocytochemistry (ICC/IF)
          COG8 Antibody in Western Blot (WB)

          Product Details

          PA5-29126

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          View 1 publication 1 publication

          Immunocytochemistry (ICC/IF)

          1:100-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human

          Published species

          Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein encompassing a sequence within the center region of human COG8. The exact sequence is proprietary.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7, with 1% BSA, 20% glycerol

          Contains

          0.01% thimerosal

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2546602

          Product Specific Information

          Recommended positive controls: 293T, A431, Raji.

          Predicted reactivity: Mouse (89%), Rat (91%), Bovine (90%).

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          Target Information

          This gene encodes a protein that is a component of the conserved oligomeric Golgi (COG) complex, a multiprotein complex that plays a structural role in the Golgi apparatus, and is involved in intracellular membrane trafficking and glycoprotein modification. Mutations in this gene cause congenital disorder of glycosylation, type IIh, a disease that is characterized by under-glycosylated serum proteins, and whose symptoms include severe psychomotor retardation, failure to thrive, seizures, and dairy and wheat product intolerance.

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: COG complex subunit 8; Component of oligomeric Golgi complex 8; conserved oligomeric golgi complex component 8; Conserved oligomeric Golgi complex subunit 8; dependent on RIC1; unnamed protein product

          View more View less

          Gene Aliases: CDG2H; COG8; DOR1

          View more View less

          UniProt ID: (Human) Q96MW5

          View more View less

          Entrez Gene ID: (Human) 84342

          View more View less

          Function(s)
          protein binding
          Process(es)
          retrograde transport, vesicle recycling within Golgi intra-Golgi vesicle-mediated transport Golgi organization protein transport glycosylation
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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