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Invitrogen
GTF2F1 Polyclonal Antibody
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Product Details
PA5-30050
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human TFIIF. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: 293T, A431, HeLa, NIH-3T3.
Predicted reactivity: Mouse (87%), Rat (87%), Rhesus Monkey (98%), Chimpanzee (97%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: General transcription factor IIF 74 kDa subunit; general transcription factor IIF polypeptide 1 (74kD subunit); General transcription factor IIF subunit 1; general transcription factor IIF, polypeptide 1, 74kDa; GTF2F1; MGC94148; OTTHUMP00000237859; TFIIF-alpha; Transcription initiation factor IIF subunit alpha; Transcription initiation factor RAP74; unnamed protein product
Gene Aliases: 2810405L04Rik; BTF4; C76800; GTF2F1; RAP74; TF2F1; TFIIF
UniProt ID: (Human) P35269, (Mouse) Q3THK3
Entrez Gene ID: (Human) 2962, (Mouse) 98053
RNA polymerase II general transcription initiation factor binding
TFIIF-class transcription factor binding
DNA binding
RNA binding
protein binding
obsolete general RNA polymerase II transcription factor activity
phosphatase activator activity
protein phosphatase binding
protein domain specific binding
promoter-specific chromatin binding
catalytic activity
transcription factor binding
poly(A) RNA binding
general transcription factor
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
response to virus
negative regulation of protein binding
positive regulation of transcription elongation from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
positive regulation of catalytic activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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