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Invitrogen
GTF2A1 Polyclonal Antibody
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Product Details
PA5-30934
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human GTF2A1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: 293T, HeLa.
Predicted reactivity: Mouse (96%), Rat (98%), Xenopus laevis (84%), Chicken (93%), Rhesus Monkey (100%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A) and several general initiation factors. One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: general transcription factor IIA 1; General transcription factor IIA subunit 1; general transcription factor IIA, 1, 19/37kDa; glucose regulated protein, 58kD pseudogene; TFIIA alpha/beta subunits; TFIIA-42; TFIIAL; Transcription initiation factor IIA subunit 1; Transcription initiation factor TFIIA 42 kDa subunit
Gene Aliases: GTF2A1; TF2A1; TFIIA; TFIIA-42; TFIIAL
UniProt ID: (Human) P52655
Entrez Gene ID: (Human) 2957
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II general transcription initiation factor binding
DNA binding
protein binding
obsolete general RNA polymerase II transcription factor activity
TBP-class protein binding
protein heterodimerization activity
RNA polymerase II sequence-specific DNA binding transcription factor binding
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter
RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of transcription initiation from RNA polymerase II promoter
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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