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Invitrogen
DCP2 Polyclonal Antibody
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FIGURE: 1 / 2
DCP2 Antibody (PA5-31091) in IHC (P)
DCP2 Polyclonal Antibody detects DCP2 protein at cytosol and nucleus on mouse testis by immunohistochemical analysis. Sample: Paraffin-embedded mouse testis. DCP2 Polyclonal Antibody (Product # PA5-31091) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-31091
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Fruit fly,
Human,
Mouse,
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human DCP2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.64 mg/mL
Amount
64 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7.
Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (86%), Xenopus laevis (86%), Rhesus Monkey (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The removal, or decapping, of eukaryotic mRNA is an important step in the degradation of mRNA. Decapping protein 2 (DCP2) is the major mRNA decapping enzyme in cells. It is a member of the Nudix hydrolases superfamily of proteins that predominantly catalyze the hydrolysis of small nucleoside diphosphate substrates linked to another moiety. DCP2 is widely expressed in multiple tissues at varying levels, with highest expression seen in testis and brain.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CG6169-PA; CG6169-PB; CG6169-PD; CG6169-PE; DCP2 decapping enzyme homolog; DCP2-PA; DCP2-PB; DCP2-PD; DCP2-PE; Decapping protein 2; DFLJ33245; hDCP2; hDpc; LP11827p; m7GpppN-mRNA hydrolase; mRNA decapping enzyme 2; mRNA-decapping enzyme 2; Nucleoside diphosphate-linked moiety X motif 20; nudix (nucleoside diphosphate linked moiety X)-type motif 20; nudix (nucleoside diphosphate linked moiety X)-type motif 20 (NUDT20); Nudix motif 20; nudix-type motif 20; SD14939p; unnamed protein product
Gene Aliases: 2410015D23Rik; 5730537H01Rik; AL118268; BEST:LD07107; CG6169; DCP2; DCp2p; dDcp; dDCP2; Dmel\CG6169; Dmel_CG6169; LD07107; NUDT20; zgc:55938; zgc:77040
UniProt ID: (Human) Q8IU60, (Mouse) Q9CYC6
Entrez Gene ID: (Fruit fly) 39722, (Human) 167227, (Mouse) 70640, (Zebrafish) 393121
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
deadenylation-dependent decapping of nuclear-transcribed mRNA
nuclear-transcribed mRNA catabolic process
regulation of cytoplasmic mRNA processing body assembly
gene silencing by miRNA
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
mRNA catabolic process
negative regulation of telomere maintenance via telomerase
regulation of mRNA stability
histone mRNA catabolic process
regulation of telomerase RNA localization to Cajal body
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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