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          • Primary Antibodies ›
          • PMS1 Antibodies

          Invitrogen

          PMS1 Polyclonal Antibody

          1 Published Figure
          1 Reference
          View all (11) PMS1 antibodies

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          Cite PMS1 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          • Published Figures (1)
          PMS1 Antibody in Western Blot (WB)
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          PMS1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          PMS1 Antibody (PA5-35952) in WB

          PMS1 Polyclonal Antibody detects PMS1 protein by western blot analysis. Various whole cell extracts (30 µg) were separated by 5 % SDS-PAGE, and blotted with PMS1 Polyclonal Antibody (Product # PA5-35952) diluted by 1:1,000. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          View Product

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          PMS1 Antibody in Western Blot (WB)
          PMS1 Antibody in Immunoprecipitation (IP)
          PMS1 Antibody in Western Blot (WB)

          Product Details

          PA5-35952

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          View 1 publication 1 publication

          Immunoprecipitation (IP)

          1:100-1:500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein encompassing a sequence within the center region of human PMS1. The exact sequence is proprietary.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.41 mg/mL

          Amount

          41 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7, with 1% BSA, 20% glycerol

          Contains

          0.025% ProClin 300

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          RRID

          AB_2553262

          Product Specific Information

          Recommended positive controls: 293T, A431, HeLa, HepG2.

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          Target Information

          This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: DNA mismatch repair protein PMS1; human homolog of yeast mutL; mismatch repair gene PMSL1; PMS1 postmeiotic segregation increased 1; PMS1 protein homolog 1; rhabdomyosarcoma antigen MU-RMS-40.10B; rhabdomyosarcoma antigen MU-RMS-40.10E; unnamed protein product

          View more View less

          Gene Aliases: HNPCC3; hPMS1; MLH2; PMS1; PMSL1

          View more View less

          UniProt ID: (Human) P54277

          View more View less

          Entrez Gene ID: (Human) 5378

          View more View less

          Function(s)
          DNA binding protein binding ATP binding ATPase activity enzyme binding mismatched DNA binding ATP-dependent DNA damage sensor activity
          Process(es)
          DNA repair mismatch repair cellular response to DNA damage stimulus response to xenobiotic stimulus
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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