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Invitrogen
ARF4 Polyclonal Antibody
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Product Details
PA5-37841
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide with sequence C-SEMTDKLGLQSLRN, from the internal region of ARF4 (aa137-150)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with rat, pig and cow based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
Target Information
ADP-ribosylation factor 1 is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. The gene products, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized as class I and class III, and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ADP ribosylation factor 4; ADP-ribosylation factor 2; ADP-ribosylation factor 4; small GTP binding protein; unnamed protein product
Gene Aliases: AA407803; ARF2; ARF4
UniProt ID: (Human) P18085, (Mouse) P61750
Entrez Gene ID: (Human) 378, (Mouse) 11843
intracellular protein transport
ER to Golgi vesicle-mediated transport
retrograde vesicle-mediated transport, Golgi to ER
epidermal growth factor receptor signaling pathway
learning
protein transport
vesicle-mediated transport
cell migration
negative regulation of apoptotic process
apical protein localization
establishment or maintenance of epithelial cell apical/basal polarity
positive regulation of transcription from RNA polymerase II promoter
response to axon injury
regulation of synapse organization
cilium morphogenesis
dendritic spine development
protein localization to cilium
regulation of postsynapse organization
regulation of cilium assembly
regulation of reactive oxygen species metabolic process
protein ADP-ribosylation
transport
small GTPase mediated signal transduction
activation of phospholipase D activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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