Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Peptide sequence: LQRQTIFNIS LMKLYNHRPL TEPSLQKTVL INNMLRRIQE ELKQEGSLRP
Sequence homology: Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 77%
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. May act as coactivator as well as corepressor of E2F1-TFDP1 and E2F4-TFDP1 complexes on E2F consensus binding sites, which would activate or inhibit E2F-target genes expression. Modulates fat storage by down-regulating the expression of key genes involved in adipocyte lipolysis, thermogenesis and oxidative metabolism. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MGC126688; MGC126690; SERTA domain-containing protein 2; Transcriptional regulator interacting with the PHD-bromodomain 2; transcriptional regulator interacting with the PHS-bromodomain 2; TRIP-Br2
Gene Aliases: KIAA0127; Sei-2; SERTAD2; TRIP-Br2; TRIPBR2
UniProt ID: (Human) Q14140
Entrez Gene ID: (Human) 9792
Molecular Function: transcription cofactor
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support