Search
Invitrogen
EMILIN1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
PA5-45673
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the C-terminal of human EMILIN1 (aa 671-720).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: QGADLADLGA TKDRIISEIN RLQQEATEHA TESEERFRGL EEGQAQAGQC
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%
Target Information
This gene encodes a protein that is one of the two components of elastic fibers. The encoded protein is rich in hydrophobic amino acids such as glycine and proline, which form mobile hydrophobic regions bounded by crosslinks between lysine residues. Deletions and mutations in this gene are associated with supravalvular aortic stenosis (SVAS) and autosomal dominant cutis laxa. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Elastin microfibril interface-located protein 1; Elastin microfibril interfacer 1; EMILIN-1
Gene Aliases: ATBFS; EMI; EMILIN; EMILIN1; gp115; HMN10; HMND10
UniProt ID: (Human) Q9Y6C2
Entrez Gene ID: (Human) 11117
aortic valve morphogenesis
cell adhesion
cell-matrix adhesion
regulation of blood pressure
positive regulation of gene expression
negative regulation of gene expression
positive regulation of cell-substrate adhesion
cell migration
negative regulation of angiogenesis
positive regulation of blood coagulation
extracellular matrix organization
negative regulation of cell migration
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of vascular endothelial growth factor receptor signaling pathway
negative regulation of collagen biosynthetic process
cell adhesion mediated by integrin
regulation of cell proliferation
positive regulation of apoptotic process
positive regulation of angiogenesis
elastic fiber assembly
negative regulation of cell activation
negative regulation of SMAD protein import into nucleus
negative regulation of ERK1 and ERK2 cascade
positive regulation of defense response to bacterium
negative regulation of vascular endothelial growth factor signaling pathway
positive regulation of extracellular matrix assembly
positive regulation of platelet aggregation
negative regulation of collagen fibril organization
negative regulation of macrophage migration
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support