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Invitrogen
Calbindin D28K Polyclonal Antibody
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Product Details
PA5-50366
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Fusion protein corresponding to a region derived from internal residues of human calbindin 1, 28kDa
Conjugate
Form
Liquid
Concentration
3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total Calbindin D protein.
Target Information
Calbindin-D-28K (also termed vitamin D-dependent calcium-binding protein, or cholecalcin), is a highly conserved 28kDa calcium binding protein, with broad tissue distribution. It belongs, together with calmodulin, S-100, parvalbumin, troponin C and other proteins, to a family of low molecular weight calcium-binding proteins (CaBPs). These CaBPs have homologous primary structures, which contain conserved polypeptide folds of the EF-hand type for Ca2+ binding. Calbindin-D-28K is found predominantly in subpopulations of central and peripheral nervous system neurons, and in certain epithelial nervous system neurons, and in certain epithelial cells involved in Ca2+ transport such as distal tubular cells and cortical collecting tubules of the kidney, and in enteric neuroendocrine cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Calbindin; calbindin 1, (28kD); calbindin 1, 28kDa; calbindin 27; Calbindin D28; calbindin-28K; calbindin-D (28k); calbindin-D28k; CalbindinD28K; D-28K; PCD-29; retrovirus-like H primer binding sequence protein; RTVL-H protein; Spot 35 protein; unnamed protein product; Vitamin D-dependent calcium-binding protein, avian-type
Gene Aliases: Brain-2; CAB27; CALB; Calb-1; CALB1; CB; D-28K
UniProt ID: (Human) P05937, (Mouse) P12658
Entrez Gene ID: (Human) 793, (Mouse) 12307
learning or memory
short-term memory
long-term memory
locomotory behavior
retina layer formation
response to auditory stimulus
metanephric part of ureteric bud development
regulation of synaptic plasticity
calcium ion homeostasis
retina development in camera-type eye
metanephric collecting duct development
metanephric distal convoluted tubule development
metanephric connecting tubule development
cochlea development
regulation of presynaptic cytosolic calcium ion concentration
regulation of postsynaptic cytosolic calcium ion concentration
regulation of cytosolic calcium ion concentration
cellular response to organic substance
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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