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Invitrogen
Nesprin 2 Polyclonal Antibody
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FIGURE: 1 / 7
Nesprin 2 Antibody (PA5-51933) in IHC
Immunohistochemical staining of Nesprin 2 in human cerebral cortex, colon, kidney and testis using Nesprin 2 Polyclonal Antibody (Product # PA5-51933) (A) shows similar protein distribution across tissues to an independent Nesprin 2 Polyclonal Antibody (B).
Product Details
PA5-51933
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human Nesprin 2. Recombinant protein control fragment (Product #RP-89127).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: NVLNDAYENL TRYKEAVTRA VESITSLEAI IIPYRVDVGN PEESLEMPLR KQEELESTVA RIQDLTEKLG MISSPEAKLQ LQYTLQELVS KNSAMKEAFK AQETEAE
Highest antigen sequence identity to the following orthologs: Mouse - 56%, Rat - 29%.
Target Information
The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: actin-binding protein; actin-binding protein associated with nuclear envelope; cytoskeletal protein; KASH domain-containing protein 2; KASH2; MGC96690; nesprin 2; Nesprin-2; nesprin-2 spectrin repeats 3-54; Nuclear envelope spectrin repeat protein 2; Nucleus and actin connecting element protein; polytrophin; Protein NUANCE; short isoform; spectrin repeat containing, nuclear envelope 2; Synaptic nuclear envelope protein 2; synaptic nuclei expressed gene 2; Syne-2; unnamed protein product
Gene Aliases: EDMD5; KASH2; KIAA1011; Nesp2; Nesprin-2; NUA; NUANCE; SYNE-2; SYNE2; TROPH
UniProt ID: (Human) Q8WXH0
Entrez Gene ID: (Human) 23224
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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