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Invitrogen
Neuroligin 1 Polyclonal Antibody
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Product Details
PA5-52323
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human NLGN1. Recombinant protein control fragment (Product #RP-88659).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DQLYLHIGLK PRVKEHYRAN KVNLWLELVP HLHNLNDISQ YTSTTTKVPS TDITFRPTRK NSVPVTSAFP TAKQDDPKQQ PSPFSVDQRD YS
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
Target Information
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC45115; Neuroligin-1; NLG 1; unnamed protein product
Gene Aliases: KIAA1070; NL1; NLG1; NLGN1
UniProt ID: (Human) Q8N2Q7
Entrez Gene ID: (Human) 22871
protein targeting
cell adhesion
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
neuron cell-cell adhesion
nervous system development
synapse assembly
positive regulation of circadian sleep/wake cycle, wakefulness
synaptic vesicle targeting
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
neuronal signal transduction
neuron projection development
positive regulation of synaptic transmission, GABAergic
protein localization to synapse
establishment of protein localization
regulation of neuron differentiation
rhythmic process
cytoskeletal matrix organization at active zone
neuron projection morphogenesis
modulation of synaptic transmission
positive regulation of filopodium assembly
positive regulation of synapse assembly
positive regulation of synaptic transmission, glutamatergic
positive regulation of dendritic spine development
negative regulation of dendritic spine morphogenesis
cellular response to calcium ion
terminal button organization
synaptic vesicle clustering
postsynaptic membrane assembly
presynaptic membrane assembly
AMPA glutamate receptor clustering
NMDA glutamate receptor clustering
neurexin clustering involved in presynaptic membrane assembly
postsynaptic density protein 95 clustering
receptor localization to synapse
NMDA selective glutamate receptor signaling pathway
AMPA selective glutamate receptor signaling pathway
presynapse assembly
neuron projection arborization
positive regulation of ruffle assembly
positive regulation of neuromuscular synaptic transmission
positive regulation of synaptic vesicle endocytosis
positive regulation of intracellular signal transduction
excitatory synapse assembly
positive regulation of synaptic vesicle exocytosis
positive regulation of excitatory postsynaptic potential
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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