Immunogen sequence: LLMDKNHAKQ QVICKLSEKV TQDFTHPPDQ SPLRPDAANR DFLSQQGKIE HLKDDMEAYR TQNCFLNSEI HQVTKIWRKV\r
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 74%.
Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Armus; BC1D2; PARIS-1; Prostate antigen recognized and identified by SEREX 1; TBC1 domain family member 2A; TBC1 domain family, member 2; TBC1 domain family, member 2A
Gene Aliases: PARIS-1; PARIS1; PP8997; TBC1D2; TBC1D2A
UniProt ID: (Human) Q9BYX2
Entrez Gene ID: (Human) 55357