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Invitrogen
Carbonic Anhydrase III Polyclonal Antibody
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Product Details
PA5-78898
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human CA3 (2-20aa AKEWGYASHNGPDHWHELF).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: SMMC Cell, HELA Cell, SW620 Cell, SCG Cell. IHC: Rat Skeletal Muscle Tissue.
Target Information
Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10. 3 kb and contains seven exons and six introns.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CA III; CA-III; CAH3; CAIII (Muscle); Carbonate dehydratase III; Carbonic anhydrase 3; Carbonic anhydrase III; carbonic anhydrase III, muscle specific; carbonic anhydrase IIII; EC 4.2.1.1; epididymis secretory sperm binding protein Li 167mP; HEL-S-167mP; unnamed protein product
Gene Aliases: BB219044; CA3; CAIII; Car-3; Car3
UniProt ID: (Human) P07451, (Mouse) P16015, (Rat) P14141
Entrez Gene ID: (Human) 761, (Mouse) 12350, (Rat) 54232
one-carbon metabolic process
response to oxidative stress
dephosphorylation
response to ethanol
skeletal muscle contraction
positive regulation of cell proliferation
response to bacterium
cellular response to insulin stimulus
response to lipid
negative regulation of apoptotic process
cellular response to leptin stimulus
cellular response to hypoxia
response to alcohol
liver regeneration
negative regulation of reactive oxygen species biosynthetic process
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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