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Invitrogen
SMU1 Polyclonal Antibody
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Product Details
PA5-54062
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SMU1. Recombinant protein control fragment (Product #RP-92934).
Conjugate
Form
Liquid
Concentration
0.40 mg/mL
Amount
40 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SIEIESSDVI RLIMQYLKEN SLHRALATLQ EETTVSLNTV DSIESFVADI NSGHWDTVLQ AIQSLKLPDK TLIDLYEQVV LELIELRELG AARSLLRQTD PMIML
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
SMU1 (suppressor of Mec8 and Unc-52 homolog), also known as BWD (brain-enriched WD), is a member of the WD-repeat SMU1 family and contains one CTLH domain, one LisH domain and six WD-repeats. SMU1 is a homolog of the C. elegans protein Smu1, a ubiquitously expressed nuclear protein that is believed to play a role in alternative splicing events of Unc-52. In mammals, SMU1 is a component of the spliceosome and appears to exhibit a conserved function, affecting the splicing of the mammalian Unc-52 homolog, namely Perlecan. Mutations in the gene encoding SMU1 may affect the function of the spliceosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Brain-enriched WD repeat-containing protein; brain-enriched WD-repeat protein; DNA replication regulator and spliceosomal factor; functional spliceosome-associated protein 57; homolog of C. elegans smu-1; smu-1 suppressor of mec-8 and unc-52 homolog; Smu-1 suppressor of mec-8 and unc-52 protein homolog; suppressor of Mec and Unc defects 1 homolog; unnamed protein product; WD40 repeat-containing protein SMU1; WD40 repeats; ubiquitin E3 ligase
Gene Aliases: 2600001O03Rik; 2610203K23Rik; AB044414; AI845086; AW556129; BWD; fSAP57; SMU-1; SMU1
UniProt ID: (Human) Q2TAY7, (Mouse) Q3UKJ7, (Rat) Q99M63
Entrez Gene ID: (Human) 55234, (Mouse) 74255, (Rat) 117541
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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