This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
PA5-29883 targets PABP in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-29883 immunogen is recombinant fragment corresponding to a region within amino acids 356 and 630 of Human PABP.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
The poly(A)-binding protein (PABP), which is found complexed to the 3-prime poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4; MIM 603407), and PABP3 (PABPC3; MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.
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Protein Aliases: cytoplasmic 2; PAB1; PABP-1; PABP1; PABPC2; PABPL1; poly A binding protein 1; poly(A) binding protein; poly(A) binding protein, cytoplasmic 1; poly(A) binding protein, cytoplasmic 2; Poly(A)-binding protein 1; Polyadenylate-binding protein 1
Gene Aliases: ePAB; PAB1; PABP; PABP1; PABPC1; PABPC2; PabpI; PABPL1