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7TM Antibodies
PAC1, PACAP Receptor 1 Polyclonal Antibody
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FIGURE: 1 / 7
PAC1, PACAP Receptor 1 Antibody (7TM0370N) in WB
Validation of the PACAP Receptor 1 in transfected HEK293 cells. Native HEK293 cells (MOCK) or HEK293 cells stably expressing the human PACAP Receptor 1 (PAC1) were lysed and immunoblotted with the phosphorylation-independent anti-PAC1 antibody (7TM0370N-IC) at a dilution of 1:1,000.
Product Details
7TM0370N
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide presents distal end of carboxyl - terminal tail of human PAC1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
Dulbecco's PBS, pH 7.4
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Alternative splicing of two exons of this gene generates four major splice variants, but their full-length nature has not been determined. PACAP receptor type 1 expression has been documented in adipose, adrenal, bone, brain, colon, ganglion, heart, lung, ovary, pancreas, placenta, spleen, and uterus. ESTs have been isolated from brain and nerve libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADCYAP1 R1; ADCYAP1R 1; adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; PAC 1; PAC1 receptor; Pac1 receptors; PACAP R 1; PACAP Receptor; PACAP receptor 1; PACAP type I receptor; PACAP-R1; PACAP/VIP receptors; PACAP1 R; PACAP1 receptor; pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop; Pituitary adenylate cyclase-activating polypeptide type I receptor; pvr1
Gene Aliases: ADCYAP1R1; PAC1; PAC1R; PACAPR; PACAPRI
UniProt ID: (Human) P41586
Entrez Gene ID: (Human) 117
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
activation of phospholipase C activity
spermatogenesis
positive regulation of calcium ion transport into cytosol
cAMP-mediated signaling
cell differentiation
positive regulation of cAMP biosynthetic process
response to estradiol
multicellular organismal response to stress
response to drug
response to ethanol
development of primary female sexual characteristics
negative regulation of cell death
positive regulation of inositol phosphate biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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